Dynamic control of NMDA receptor Ca2+ permeability by endogenous and synthetic modulators

Proceedings of the National Academy of Sciences, Volume 122, Number 42, October 2025.
ImportanceNMDA receptors conduct Ca2+-rich excitatory currents, which are essential for learning and memory, and are responsible for serious neuropsychiatric disorders. Drugs acting on the NMDA receptor are currently being tested for their ability to control…