Enhanced PIEZO1 function contributes to the pathogenesis of sickle cell disease
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, Volume 122, Number 40, October 2025.
SignificanceSickle cell disease (SCD) is a life-limiting genetic disease characterized by dehydration, hemolysis, and inflammation of red blood cells. The mechanosensitive ion channel PIEZO1 regulates red blood cell volume, but its role in SCD remains unclear. …
