Exceptional diversity of allorecognition receptors in a nonvertebrate chordate reveals principles of innate allelic discrimination

Proceedings of the National Academy of Sciences, Volume 122, Number 43, October 2025.
ImportancePolymorphic self/non-self discrimination systems are found throughout metazoans, with discriminatory capacities reminiscent of the adaptive immunity of vertebrates. However, there is no conservation of allorecognition genes between phyla and…