Extracellular stiffness regulates cell fate determination and drives the emergence of evolutionary novelty in the teleost heart

Proceedings of the National Academy of Sciences, Volume 123, Issue 8, February 2026. <br/>SignificanceThe acquisition of new phenotypic traits is a key driver for a diversification of life. While genetic underpinnings of such traits have been well studied, the contribution of physical properties remains elusive. Here, we show that …