Microvascular architecture and physiological fluctuations constrain the control of cerebral microcirculation

Proceedings of the National Academy of Sciences, Volume 123, Issue 3, January 2026. <br/>SignificanceThe vasculature in the brain forms a multiscale network that actively regulates blood flow to support brain health. To determine how brain angioarchitecture defines physiological limits on the control of cerebral microcirculation, we …