T-cadherin, a major adiponectin binding partner, suppresses ERK signaling in metabolic tissues

Proceedings of the National Academy of Sciences, Volume 123, Issue 8, February 2026. <br/>SignificanceT-cadherin, which is a major adiponectin binding partner, exerts various organ-protective effects. We demonstrated that T-cadherin suppresses ERK signaling in both cultured cells and murine tissues. T-cadherin knockdown increased ERK …