Genetics of prelingual isolated deafness and Usher syndrome in the Maghreb and Jordan: Harnessing the potential of homozygosity

Proceedings of the National Academy of Sciences, Volume 122, Issue 50, December 2025. <br/>SignificanceHomozygosity for causal mutations in recessive deafness provides a unique opportunity to unravel the mutation/phenotype relationship. By studying familial congenital sensorineural deafness in highly consanguineous populations in North Africa, …