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Glycosaminoglycans activate peptidylarginine deiminase 4 by enhancing calcium affinity

https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c

Proceedings of the National Academy of Sciences, Volume 122, Issue 44, November 2025. <br/>SignificanceRheumatoid arthritis is an autoimmune disease characterized by the presence of antibodies against citrullinated epitopes. The source of such peptides and trigger leading to the disease onset are still under debate. In this paper, we show that …

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