Glycosylation of GETV E2 promotes pathogenesis in animal models

Proceedings of the National Academy of Sciences, Volume 123, Issue 1, January 2026. <br/>SignificanceGetah virus (GETV), an emerging mosquito-borne pathogen, poses a growing threat to livestock and public health. We identified the glycosylation at the E2-N262 site of GETV as a key evolutionary adaptation. Using reverse genetics, biochemical …