Guanine storage vacuoles sequester guanine crystals and serve as nitrogen reserves in Chlamydomonas reinhardtii

Proceedings of the National Academy of Sciences, Volume 122, Issue 41, October 2025. <br/>SignificanceA new organelle, the guanine storage vacuole (GSV), is described using quick-freeze deep-etch electron microscopy, a technique that preserves its membrane ultrastructure, its endowment of crystalline guanine, and its morphological changes …