HLA-B*15:01-positive severe COVID-19 patients lack CD8+ T cell pools with highly expanded public clonotypes

Proceedings of the National Academy of Sciences, Volume 122, Issue 36, September 2025. <br/>SignificanceUnderstanding factors driving asymptomatic versus severe disease is of key importance if we are to control emerging and re-emerging viral infections. As preexisting CD8+T-cell responses have been associated with asymptomatic COVID-19 in …