HLA-DQB1*03:01 strongly affects age of onset of type 1 narcolepsy independently of DQA1 and ethnicity
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Proceedings of the National Academy of Sciences, Volume 122, Number 50, December 2025.
ImportanceNarcolepsy type 1 is notable for its strong transethnic association with human leukocyte antigen (HLA) -DQA1*01:02/DQB1*06:02; only a handful of cases without these alleles have been found. HLA-DQA1 variation eliminates susceptibility,…
