Identifying direct risk factors in UK Biobank via simultaneous Bayesian-frequentist model-averaged hypothesis testing using Doublethink

Proceedings of the National Academy of Sciences, Volume 123, Issue 1, January 2026. <br/>SignificanceUnderstanding what causes disease is key to improving its treatment and prevention. Large health studies like UK Biobank measure thousands of possible causes of disease. Traditionally, scientists have tested possible causes (like smoking or …