Indiana vs. Michigan State prediction, odds, time: 2026 college basketball picks from proven model

Two Big Ten blue bloods will meet Sunday on CBS and Paramount+ when the Michigan St. Spartans visit the Indiana Hoosiers. No. 13 MSU (23-5, 13-4 Big Ten) has won three straight games, most recently beating Purdue 76-74 on Thursday. The Hoosiers (17-11, 8-9 Big Ten) have lost three straight games overall and are coming off a 72-68 loss Tuesday to Northwestern. MSU leads the all-time series 27-18.

The announcement will take place at 3:45 p.m. ET from Assembly Hall in Bloomington, Indiana. The Spartans triumphed 81-60 when these teams met in Michigan on January 13. The Spartans are 2.5-point favorites in the latest Indiana vs. Michigan State odds, while the over/under in total points scored is 144.5. Before making any Michigan State vs. Indiana college basketball picks, check out men’s college basketball predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every college basketball game 10,000 times and enters Week 17 on a torrid 11-1 streak on its top-rated over/under college basketball picks dating back to last season, and is on a 20-11 run on the CBB’s top-rated side picks. Anyone who followed his college basketball betting tips on sportsbooks and betting apps could have seen solid returns.

Today, the model simulated Michigan State vs. Indiana 10,000 times and just revealed its coveted men’s college basketball picks and betting predictions. You can now head over to SportsLine to see the model’s choices. Here are several men’s college basketball odds and men’s college basketball betting lines for Indiana vs. Michigan State:

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Best Indiana vs. Michigan State Predictions

SportsLine’s model has simulated Michigan State vs. Indiana 10,000 times and is exceeding the total (144.5 points). Totals in the mid-140s like this have leaned for the Spartans as the Over is 4-2 while the O/U is between 142 and 147 this season. MSU has also engaged in high-scoring games against defensively struggling teams as Michigan State has eclipsed the total in five of six road games against teams allowing more than 72 points per game, with IU giving up 72.1 points per game.

The Over is 7-1 overall in Michigan State’s last eight games, while Ohio State has seen the Over go 4-3 in their last seven matchups. Both teams should have four double-digit scorers, with each team allowing several more points than they give up on average. The teams combine for 151 points, according to simulations, with the Over reaching 63.1% of simulations.

How to make choices between Michigan State and Indiana

The model also indicates that one side of the gap hits almost 60% of the time. You can only see this pick on SportsLine.

So who does Indiana win against Michigan State, and which side of the spread hits in nearly 60% of simulations? Visit SportsLine now to see which way Michigan State vs. Indiana went, all from the advanced model that has simulated this game 10,000 times, and find out.