Novel compound attacks tuberculosis bacteria's ATP synthase, showing promise against drug resistance

Researchers at Martin Luther University Halle-Wittenberg (MLU) have developed a promising new substance to target the bacteria that causes tuberculosis. The team produced a compound that inhibits the pathogens’ ability to produce energy and causes them to die. Established drugs work the same way, but the pathogen becomes increasingly resistant to these drugs. The study was carried out jointly with other researchers from Germany, the United States and Canada and its results were published in the Journal of Medicinal Chemistry.