Isoform-specific regulation of PKM by acetylation
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, volume 122, number 48, December 2025.
ImportancePyruvate kinase (PK) catalyzes the final step of glycolysis, the pathway by which glucose is metabolized. In humans, the M1 isoform of PK (PKM1) is constitutively active, but the activity of the highly homologous PKM2 isoform is regulated by, …
