Lysosomal reduced thiols are essential for mouse embryonic development

Proceedings of the National Academy of Sciences, Volume 122, number 36, September 2025.
Simply study of the cysteine ​​lysosomal import system was limited until the discovery of a key component, the MFSD12 transmembrane protein. Here, we have genetically disturbed the mice mouses and found that it is essential for organogenesis. Parallel …