Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation | Science

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Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation | Science
Transcriptional adaptation (TA) is a mechanism of genetic robustness by which the decay of mutant messenger RNA (mRNA) induces sequence-dependent upregulation of so-called adaptive genes. How cytoplasmically generated mRNA fragments affect the nucleus…

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