Merkel cell mechanotransduction facilitates adult neurogenesis and cognition in an enriched environment

Proceedings of the National Academy of Sciences, Volume 122, Issue 51, December 2025. <br/>SignificanceTactile perception reshapes the brain when exploring a novel environment. Our study has demonstrated that Piezo2-mediated Merkel cell mechanotransduction facilitates environmental enrichment-induced neurogenesis and cognitive enhancement. This …