A systems approach identifies MERTK as a therapeutic vulnerability in ZFTA-RELA-driven ependymomas
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, Volume 123, Number 7, February 2026.
Significance ZFTA-RELA (Zinc Finger Translocation Associated – RELA Proto-Oncogene) fusion-positive ependymomas are fatal pediatric brain tumors lacking targeted therapies. By integrating human tumor transcriptomics on a large scale, a genetically modified system…
