Multiscale mitochondrial cristae remodeling links Opa1 downregulation to reduced OXPHOS capacity in aged hearts
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, Volume 123, Number 1, January 2026.
ImportanceMitochondrial cristae are specialized subcompartments of the inner mitochondrial membrane where oxidative phosphorylation (OXPHOS) occurs, providing energy for cardiac function. This study reveals that the integrity of the ridges is disrupted in…
