Ena/VASP-EVH1 inhibition prevents chemotaxis and metastasis by blocking the EVH1–WAVE2 interaction

Proceedings of the National Academy of Sciences, Volume 122, Issue 26, July 2025. <br/>SignificanceProtein–protein interactions mediated by proline-rich motifs (PRMs) play a crucial role in regulating important cellular signaling cascades associated with metastasis of malignant tumors and related death. Here, we show that the interaction …