Mycophenolic acid treatment drives the emergence of novel SARS-CoV-2 variants

Proceedings of the National Academy of Sciences, Volume 122, number 28, July 2025.
Significant acid (MPA), an immunosuppressant widely used in post-transplantation regimes, has antiviral activity by exhausting triphosphate cell guanosine, which inhibit viral replication. However, prolonged exposure to the MPA can drive …