Next-gen interferometric diffusing wave spectroscopy achieves 20x signal boost in cerebral blood flow monitoring

Cerebral blood flow is essential for normal brain function and is often disrupted in neurological disease. If a coherent light source is projected onto perfused tissue, the detected spots, or “grains” of light, fluctuate, or “dance,” at a speed proportional to the blood flow in the volume sampled by the light. In brain tissue, this concept can be exploited to measure cerebral blood flow index (CBFi).