NFL odds, betting lines, spreads: Week 12 picks, predictions, best bets today


The NFL Week 12 odds feature four games with a spread of less than a field goal, while three contests have an NFL line in double digits. Among the frontrunners are the Steelers at Bears (-2.5), with Aaron Rodgers (wrist) out and Mason Rudolph starting, and the Jaguars at Cardinals (+2.5), while double-digit favorites to place Week 12 NFL bets include Seattle (-12.5) at Tennessee and Detroit (-13.5) at the Giants, with New York again without Jaxson Dart (concussion). However, a team that isn’t even over .500 is tied for the biggest favorite in the Week 12 NFL schedule.
Baltimore has won four straight to get back into the playoff race, and they will host the Jets on Sunday. The Ravens are at -13.5 to use in Week 12 NFL picks, and while double-digit favorites are 10-1 this season, they are just 6-5 ATS. One such game where the spread falls between the aforementioned extremes is Chiefs vs. Colts, who have another .500 team in Kansas City as a 3.5-point favorite over an 8-2 Colts team coming off a bye. All updated Week 12 NFL lines are listed below, and SportsLine’s advanced computer model has all the NFL betting tips and NFL predictions you need to make the best Week 12 NFL picks now.
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The model, which simulates every NFL game 10,000 times, costs well over $7,000 for $100 players among the NFL’s top-rated picks since its inception. The model enters Week 12 with a 48-33 record on top-rated picks dating back to 2024. Anyone tracking their NFL betting picks at sportsbooks and betting sites could have seen solid returns.
Now he has turned his attention to the latest NFL Week 12 odds and NFL betting lines and has locked in the betting picks for every NFL game. Head here to see each choice.
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Best NFL Predictions for Week 12
We can tell you that one of the model’s strongest picks for NFL Week 12 is the Cardinals (+2.5, 47.5) covering at home against Jacksonville in a Sunday 4:05 p.m. ET kickoff. Arizona is 6-1 ATS against AFC opponents since 2024, which is the second-best ATS record for any team in non-conference matchups. Meanwhile, the Jags are just 1-4 ATS this year outside of Jacksonville, and the takeaways that fueled their early success have all but dried up. The Jaguars averaged 3.3 turnovers in their first four games, but have averaged just 0.8 forced turnovers per game in their last six. So, extra offensive possessions for Arizona allow it to take advantage of the Jags’ 26th-ranked pass defense, as Jacoby Brissett should have more yards and touchdowns than Trevor Lawrence. With that, the Cardinals are covering over 50% of simulations. Find out which other teams to choose here.
Another one of its Week 12 NFL predictions: the Ravens (-13.5, 44.5) cover versus the Jets in well over 50% of simulations. New York is coming off a mini-bye, having played last Thursday, but there’s no spread advantage with this rest edge. The Jets are 3-11-1 ATS over their last 15 games when they have a rest advantage over their opponent. Their Sunday opponent, Baltimore, has recently looked like the team most expected them to be all season as the Ravens have allowed just 14.8 points over their last five games. That includes a pair of games versus top-10 scoring offenses, but the team doesn’t have to worry about seeing that with the Jets, who rank dead last in passing offense and 25th in scoring. Baltimore covers with points to spare, and the model also says the Over hits in over 70% of simulations. See which other teams to pick here.
How to make Week 12 NFL picks
The model has also made the call on who wins and covers in every other game on the Week 12 NFL schedule and just revealed five teams projected to win by double-digits, potentially giving you a huge payday by playing the alternate lines. You can only get every pick for every game at SportsLine.
So what Week 12 NFL picks can you make with confidence, and which five teams should you lock in now? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $7,000, and find out.
Week 12 NFL betting odds, lines, live spreads, scores
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