Nitric oxide promotes rapid development of motility to accelerate biofilm dispersal in Vibrio cholerae

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Proceedings of the National Academy of Sciences, Volume 122, Number 49, December 2025.
Significance Biofilm dispersal is a critical but poorly understood step in the life cycle of bacterial pathogens. We identify nitric oxide (NO), a host immune signal, as a rapid and specific trigger of biofilm dispersal in Vibrio cholerae. Unlike…

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