College football odds, picks, lines, spreads: 2025 Rivalry Week predictions, best bets today
There’s no better time to make college football choices than during Rivalry Week, which is full of fierce foes battling it out. From Ohio State vs. Michigan (+10) to Alabama vs. Auburn (+5.5) to Virginia vs. Virginia Tech (+8.5), many can place Week 14 college football bets with their hearts as well as their heads. Not only can you make picks on these conference games, but a number of non-conference contests could be factored into your college football betting strategy. South Carolina is a 2.5-point favorite over Clemson, according to the latest Week 14 college football odds, in an SEC vs. ACC battle.
Others of this ilk include Florida vs. Florida State (+1.5) and Kentucky vs. Louisville (-1.5). Meanwhile, no team has performed better in college football picks against the spread than Texas Tech, which is 10-1 against the line. The Red Raiders are 23.5-point favorites over West Virginia as the former look for a win to secure their first-ever trip to the Big 12 Championship Game. Before you lock in any Week 14 college football picks, be sure to check out the latest Week 14 college football predictions from SportsLine’s proven model.
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The model simulates each FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college football picks. Anyone tracking their college football betting picks at sportsbooks and betting sites could have seen some solid returns.
Now he has turned his attention to the latest college football odds and Week 14 college football betting lines on the spread, money line and over/under. Head here to see each choice.
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Best College Football Predictions for Rivalry Week
One of the college football picks the model is leading on in Week 14: Florida (-1.5, 49.5) covers against Florida State in Saturday’s 4:30 p.m. ET kickoff nearly 60% of the time. The Gators have been much more competitive since Billy Napier’s firing, as the team has as many ATS wins (two) in four games under Billy Gonzales’s interim leadership as in seven games under Napier. Florida won last year’s game — by 20 points on the road — and hosting this year’s contest gives it a huge advantage. The Seminoles haven’t won or covered in an away stadium since 2023 as they are 0-8 both straight and against the spread in this run. In addition to Florida coverage, the model predicts that the Under will reach over 60% of simulations. Find out what other choices the model likes here.
Another prediction: Virginia Tech (+8.5, 52.5) covers on the road versus No. 17 Virginia at 7 p.m. ET on Saturday. It’s impossible to ignore the outright dominance of the Hokies over their in-state rival in this series, as Virginia Tech has won 19 of its last 20 games versus Virginia Tech. The last few matchups haven’t even been close, as Virginia Tech won by 20 points at home last year and prevailed by 38 points the last time UVA hosted in 2023. This year, the Hokies have played much better under interim coach, Philip Montgomery, as they’ve both outright won and covered three times under him, compared to being winless both straight up and ATS under former coach Brent Fry. UVA has dropped two straight at home ATS as the model forecasts this as a one-score game. The model projects the Hokies to cover well over 50% of the time. See the rest of the model’s picks here.
How to make college football picks for Week 14
The model has also made the call on who wins and covers in every FBS matchup in Week 14, and it’s identified several A-rated picks involving major games. You can only get every pick for every game at SportsLine, and for a limited time you can use promo code CHAMPIONSHIP to get your first month at SportsLine for $1.
So what college football picks can you make with confidence, and which A-rated picks should you jump on? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $2,000 in profit since its inception, and find out.
Week 14 college football odds for notable games
See full Week 14 college football picks, odds, predictions here
(odds subject to change)
Ohio State vs. Michigan (+10, 43.5)
Clemson vs. South Carolina (-2.5, 46.5)
Miami vs. Pitt (+7, 49.5)
LSU vs. Oklahoma (-10.5, 36.5)
Vanderbilt vs. Tennessee (-2.5, 66.5)
Oregon vs. Washington (+7, 51.5)
Florida State vs. Florida (-1.5, 49.5)
Alabama vs. Auburn (+5.5, 46.5)
UCLA vs. USC (-21.5, 58.5)
Notre Dame vs. Stanford (+32.5, 49.5)
