Prairie View A&M vs. Lehigh prediction, odds, spread, time: 2026 First Four picks from proven model

The Prairie View A&M Panthers take on the Lehigh Mountain Hawks in a 2026 First Four game Wednesday night. The winner will be the 16th seed and will face the top-seeded Florida Gators on Friday. The Mountain Hawks (18-16) won the Patriot League championship tournament on Wednesday by beating Boston University 74-60, while the Panthers (18-17) won the SWAC tournament by beating Southern 72-66 on Saturday. The Mountain Hawks have won eight of their last 10 games. The Panthers have won nine of their last 10 games.

Tip-off from UD Arena in Dayton, Ohio, is scheduled for 6:40 p.m. ET. Prairie View A&M will face Lehigh for the first time on Wednesday. Both teams enter the tournament having won five straight. Lehigh is a 3.5-point favorite in the latest Prairie View A&M vs. Lehigh odds, while the over/under in total points scored is 142.5. Before making any Lehigh vs. Prairie View A&M picks, check out men’s college basketball predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times. He entered the tournament on a torrid 11-1 streak on his highest-rated over/under college basketball picks dating back to last season, and is on a 28-22 streak on the highest-rated picks on the CBB side. Anyone who followed his college basketball betting tips on sportsbooks and betting apps could have seen solid returns.

Now, the model has simulated Prairie View A&M vs. Lehigh 10,000 times and just revealed its top four picks and betting predictions for 2026. You can head over to SportsLine now to see the model’s picks. Here are several men’s college basketball odds and men’s college basketball betting lines for Lehigh vs. Prairie View A&M:

Best Predictions Prairie View A&M vs Lehigh

After 10,000 simulations of Prairie View A&M vs. Lehigh, SportsLine’s model is exceeding the total (143.5 points). Prairie View A&M is 10-0 ATS in their last 10 games and 6-0 ATS in their last six games when playing as an underdog.

The model projects the Panthers to have four players scoring 12.4 points or more, including Dontae Horne, who is projected to score 21.5 points. The Mountain Hawks should have four players scoring 10.6 points or more, led by Nasir Whitlock, who should score 23.9 points. The model projects a combined 151 points while the Over fades in 70% of simulations.

How to make choices Prairie View A&M vs. Lehigh

The model also indicates that one side of the gap hits well over 50% of the time. You can only see this pick on SportsLine.

So who wins Prairie View A&M vs. Lehigh, and which side of the spread reaches well over 50% of simulations? Visit SportsLine now to see which side of the spread to be on, all from the advanced model that has simulated this game 10,000 times, and find out.