Predicting individual incubation of opioid craving by whole-brain functional connectivity

Proceedings of the National Academy of Sciences, Volume 123, Issue 11, March 2026. <br/>SignificanceRelapse driven by craving is a central challenge in treating opioid addiction. Using resting-state fMRI and connectome-based predictive modeling, we identified a whole-brain connectivity pattern that predicted incubation of oxycodone craving …