Programmable immunoprobiotics orchestrate antitumor immune response with Pin1 inhibition for pancreatic cancer treatment

Proceedings of the National Academy of Sciences, Volume 122, number 34, August 2025.
The cancer of the service of the period is among the deadliest cancers due to its dense fibrotic tumor microenvironnement and the immune response suppressed. We have developed intelligent probiotic therapy using engineering colibacteria which delivers a pine inhibitor1 —…