Protein synthesis blockade prevents fear memory reactivation via inhibition of engram synapse strengthening

Proceedings of the National Academy of Sciences, Volume 123, Issue 3, January 2026. <br/>SignificanceMemory is not stored solely within specialized engram “cells” but also in the dynamic connections between them called engram synapses. Our study shows that the formation and maintenance of these synapses depend on protein synthesis. Notably, …