Rams vs. Falcons prediction, odds: ‘Monday Night Football’ picks from 10,000 simulations

The final “Monday Night Football” game of the 2025 NFL regular season will take place in Week 17 as the Los Angeles Rams visit the Atlanta Falcons. The Rams (11-4) just lost Thursday to Seattle, 38-37 in overtime, but Los Angeles has already clinched a playoff spot. The Falcons (6-9) were eliminated from the playoffs, but have won two straight, last beating Arizona, 26-19. The Rams lead the all-time series 49-30-2.

Kickoff will be at 8:15 p.m. ET from Mercedes-Benz Stadium in Atlanta. LA has won the last two matchups, with the most recent meeting taking place in 2022. DraftKings Sportsbook’s latest Falcons vs. Rams has Los Angeles as a 7.5-point road favorite, while the over/under in total points scored is 49.5. Before making any Rams vs. Falcons picks, be sure to check out the NFL predictions from SportsLine’s projection model.

The model, which simulates every NFL game 10,000 times, costs well over $7,000 for $100 players among the NFL’s top-rated picks since its inception. The model enters Week 17 with a 53-37 record on top-rated picks dating back to 2024. Anyone tracking their NFL betting picks at sportsbooks and betting sites could have seen strong returns.

Now the model has focused on Atlanta vs. Los Angeles. You can head to SportsLine now to see his picks. Here are several NFL odds and betting lines for the Rams vs. Falcons:

Why the Rams can cover

No team has a better record than Los Angeles with an 11-4 record, which includes three straight coverages and a 5-1 ATS mark as a road favorite. The Rams lead the league in offense, with the No. 6 defense to boot, making them one of two teams to rank in the top six in both cases. Matthew Stafford is the MVP favorite because he has both the highest touchdown percentage and lowest interception rate. He’s complemented by the No. 5 rushing attack, and the ground game should succeed against an Atlanta run defense that ranks 25th in yards allowed and yards per carry given up. Find out which team to support on SportsLine.

Why the Falcons can cover

The Falcons are coming off two straight road wins and now return home, where they have won four of their last five meetings with the Rams. Kirk Cousins ​​has brought stability to the offense, while Bijan Robinson has his sights set on Offensive Player of the Year. He leads the league with 2,026 yards from scrimmage, and he’s averaging nearly 100 yards rushing, plus over 50 yards receiving over his last six games. Additionally, the Rams defense has been leaky as of late, as the two highest point totals it has allowed all season have come in the last two weeks. Finally, LA is just 4-7 ATS in its last 11 games with an advantage at rest, entering a Thursday matchup. Find out which team to support on SportsLine.

How to make Falcons vs. Rams picks

For the Rams against the Falcons on “Monday Night Football,” the model leans toward the total, projecting 52 combined points. It also indicates that one side of the gap hits more than 50% of the time. See what it’s like on SportsLine.

Who wins the Rams against the Falcons, and which side of the spread hits in more than 50% of simulations? Visit SportsLine now to see which side of the Falcons vs. Rams spread you should jump to, all from the model that’s 53-37 on top-rated picks since 2024and find out.