Regulation of an lncRNA irf8 by the Ikzf1/Myb complex drives neutrophil development
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, Volume 122, Number 41, October 2025.
Significance Our study uncovered a mechanism by which Ikzf1 and Myb cooperatively regulated neutrophil and macrophage engagement in myeloid progenitors via lncRNAirf8-2. By modulating irf8 dosage via Zfp36l1, irf8-2 biased neutrophil fate,…
