S-nitrosylation of pVHL regulates β2 adrenergic receptor function

Proceedings of the National Academy of Sciences, Volume 122, Issue 37, September 2025. <br/>SignificanceThe β2adrenergic receptor (β2AR), the prototypic G protein–coupled receptor (GPCR), controls critical cardiopulmonary physiology, with an exemplary role in regulating airway tone. Basal expression of the β2AR is regulated by the ubiquitin …