Single-cell analyses identify independent aging processes that compete to determine cellular fate in budding yeast

Proceedings of the National Academy of Sciences, Volume 123, Issue 11, March 2026. <br/>SignificancePhenotypic heterogeneity underlies aging, yet its molecular basis remains obscure. Using single-cell transcriptomics and longitudinal imaging inSaccharomyces cerevisiae, we systematically untangled independent aging pathways. We establish …