Loss of vitamin C biosynthesis protects from the pathology of a parasitic infection

Proceedings of the National Academy of Sciences, Volume 122, Issue 52, December 2025. <br/>SignificanceAscorbate synthesis was lost in the evolution of several species, turning this molecule into an essential micronutrient, vitamin C. Are there any benefits to losing ascorbate synthesis and becoming prone to ascorbate deficiency? We show that …