Convergence of external and internal stressors on a stress-responsive enhancer of the Sonic hedgehog gene to induce hair disorders

Proceedings of the National Academy of Sciences, Volume 123, Issue 14, April 2026. <br/>SignificanceIt is conceivable that stress impacts our health through perturbation of the intrinsic regulatory molecular pathways. Here, we used the fast-growing hair follicles as a model, and showed that various stressors suppress the expression ofSonic …