Structural basis for Lamassu-based antiviral immunity and its evolution from DNA repair machinery

Proceedings of the National Academy of Sciences, Volume 122, Issue 47, November 2025. <br/>SignificanceLamassu is a widespread antiviral system in bacteria that uses structural maintenance of chromosomes-like proteins, typically associated with chromosome maintenance, to detect and halt phage infection. By solving cryo-EM structures of the …