Spatial transcriptomics reveals tumor microenvironment–driven subtypes of invasive lobular carcinoma

Proceedings of the National Academy of Sciences, Volume 123, Issue 6, February 2026. <br/>SignificanceThe tumor microenvironment (TME) of invasive lobular carcinoma (ILC) remains largely unexplored despite its clinical relevance and distinct biology. Using spatial transcriptomics, we reveal insights into ILC spatial architecture and identify …