STING single amino acid polymorphisms modulate iridovirus immune evasion and pathogenicity spectrum

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Proceedings of the National Academy of Sciences, Volume 123, Number 4, January 2026.
SignificanceThis study reveals the molecular mechanism by which fish iridovirus ISKNV manages to evade the immune system through targeted regulation of the stimulator of interferon genes-interferon pathway via single amino acid polymorphisms (SAPs) at K315/…

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