Structures of folding intermediates on BAM show diverse substrates fold by a conserved mechanism

Proceedings of the National Academy of Sciences, Volume 123, Issue 14, April 2026. <br/>SignificanceThe outer membrane of Gram-negative bacteria contains a wide variety of integral β-barrel proteins. Here, we study the conserved β-barrel assembly machine which is responsible for folding and inserting these membrane β-barrels. By determining …