Subcellular calcium dynamics and organelle perturbations in resistosome-mediated cell death

Proceedings of the National Academy of Sciences, Volume 123, Issue 12, March 2026. <br/>SignificanceNucleotide-binding leucine-rich repeat (NLR) proteins form resistosomes to trigger immune responses, yet how resistosome activation leads to cell death has remained unresolved. By live-cell imaging of NLR required for cell death 4 (NRC4) …