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Variable thresholds for phosphorylation targets of the ERK signaling pathway

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Proceedings of the National Academy of Sciences, Volume 123, Issue 6, February 2026. <br/>SignificanceA well-known observation that has never been fully explained is that cells respond differently to changes in the strength of mitogen-activated protein (MAP) kinase signaling through the extracellular signal-regulated kinase (ERK) pathway. For …

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