The intestinal environment potentiates bacteriophage adaptation in response to phenotypic resistance in Salmonella Typhimurium

Proceedings of the National Academy of Sciences, Volume 122, Issue 41, October 2025. <br/>SignificanceUnderstanding phage–bacteria coevolution is critical for the design of robust phage-based therapy. Heterogenous expression of surface glycan modifications known as phase variation allows populations ofSalmonellaTyphimurium to include both …