Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans | Science

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Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans | Science
A main HIV vaccination strategy requires a priming immunogen to induce largely neutralizing antibody precursors (BNAB), followed by a series of heterologous boosters to cause a somatic hypermutation (SHM) and produce BNAB. In two randomized albums …

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