Week 1 NFL odds, lines, betting picks, spreads: 2025 predictions: Computer model backing Packers, Bengals


The NFL 1 Calendar of the NFL 1 continues on Sunday, and some of the tightest NFL ratings include Steelers VS Jets (+3), Rams VS Texans (+3), VS Lions Packers (+1.5) and the 49ers vs Seahawks (+1.5). There are only two competitions with the NFL spreats of the NFL of week 1 on a touchdown, including when the choice n ° 1 CAM WARD makes its professional debut because its titans are 8.5-point outsiders in BO NIX and the broncos, making the biggest outsider of the NFL which remains at the pension this weekend. Whatever the NFL betting trends that you decide to follow for the list of opening matches, you certainly want your football bets to launch the 2025 NFL season to start on the right note.
All the NFL lines of the week 1 Updates are listed below, and the advanced computer model of Sportsline has all the advice of Paris NFL and the predictions of the NFL you need to make the best choices of the NFL of the week 1 now. Bet on each game of the NFL Week 1 at Draftkings Sportsbook, where new users can target the Draftking promotional codewhich instantly offers $ 300 from Paris Bonus plus more than $ 200 of NFL Sunday tickets:
The model, which simulates each game of the NFL 10,000 times, is up much more than $ 7,000 for $ 100 players on the most rated NFL choices since its creation. The model went 31-15 on the most rated choices in 2024. Anyone according to its Paris choices on the NFL on Sportsbooks and on Paris sites could have seen strong returns.
Now he turned his attention to the last NFL nfl lines of the week 1 and Paris NFL and locked the choices of Paris for each NFL match. Head here to see each choice. New users can also bet for week 1 from NFL to BET365 and get $ 200 from Paris Bonus instantly:
Top Week 1 NFL Predictions
We can tell you that one of the choices of the strongest NFL of week 1 of the model is that Bengals (-5.5, 48) cover propagation on the road compared to brown. Joe Flacco will be under the center of Cleveland, and the 40 -year -old lost three consecutive departures against Cincinnati. Meanwhile, Joe Burrow led the league in the two yards by the pass (4,918) and the passing affected (43) a year ago, when he became the third player in the history of the NFL to have at least 4,500 yards, 40 affected and less than 10 interceptions. After having signed both Ja’marr Chase and Tee Higgins to the extensions of this off -season, the passage offensive n ° 1 of the League a year ago returns intact.
Cincy’s passenger game, alone, could put more points on the game than Cleveland, which ranked at the end of Dead-Lest in 2024. Cleveland fought in all facets, with the last third attack, committing the second most important reversals, and having classifications at the end of five in the precipitated offensive and the Redzone score. In addition, the defense of the Browns slipped considerably from the unit which led the NFL in yards authorized in 2023 while Cleveland ranked 27th in points authorized in 2024. The model projects Cincy (-5.5) to save more than a touchdown and to cover much more than 50% of the time. See which other teams to choose here.
Another one of its Week 1 NFL predictions: the Packers (-1.5, 47.5), who are expected to have new acquisition Micah Parsons in the lineup, cover at home versus the Lions. The line has moved one point in favor of Green Bay since the Parsons trade news broke The Commanders may have revealed the blueprint to exploiting Detroit, courtesy of Washington’s road playoff win last season. Jared Goff was often pressured, which led to him turning the ball over four times, and few teams apply pressure or create takeaways quite like Green Bay. It ranked fourth in turnovers created a year ago, and just seven teams racked up more sacks, despite the Packers blitzing at the second-lowest rate in the league.
One also can’t forget the offseason attrition for Detroit, which lost both of its coordinators, as well as three-time All-Pro center Frank Ragnow. The Packers, meanwhile, added the one thing it was missing in a No. 1 wideout by drafting Matthew Golden in the first round. The model projects him to make an immediate impact by leading the Packers in receiving in Week 1, while Green Bay’s defense has both more sacks and more takeaways than Detroit on defense. With that, the Packers cover nearly 60% of the time, with the Over (47.5) hitting in more than 50% of simulations. See which other teams to pick here.
How to make Week 1 NFL picks
The model has also made the call on who wins and covers in every other game on the Week 1 NFL schedule and just revealed three underdogs that outright win, potentially giving you a huge payday. You can only get every pick for every game at SportsLine.
So what NFL picks can you make with confidence, and which three teams should you lock in now? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $7,000, and find out.
Week 1 NFL betting odds, lines, live spreads, scores
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