Hopx(+) optic nerve head-astrocytes counter neuronal stress and glaucoma damage

Proceedings of the National Academy of Sciences, Volume 123, Issue 18, May 2026. <br/>SignificanceRetinal ganglion cell (RGCs) axons form the optic nerve (ON), and are subjected to multiple stressors that can result in ON damage. We define a group of Hopx(+) expressing astrocytes in the rodent ON, localized to the ON head (ONH), that are …