Mot1 regulation of promoter binding by TBP varies with stress and gene expression levels independently of coactivator dependence

Proceedings of the National Academy of Sciences, Volume 122, Issue 42, October 2025. <br/>SignificanceEfficient transcription requires recycling of TATA-binding protein (TBP) from nonproductive DNA binding sites by essential ATPase Mot1. Mot1 was believed to preferentially dissociate TBP from promoters of stress-induced genes that utilize …