2026 NFL Wild Card Weekend picks, AI-generated score predictions, best bets
The 2026 NFL Wild Card Weekend schedule includes two games on Saturday, three on Sunday and a “Monday Night Football” matchup between the Houston Texans and Pittsburgh Steelers. Monday’s intriguing matchup pits quarterback CJ Stroud and the Houston Texans against 21-year veteran Aaron Rodgers and the Pittsburgh Steelers. The Texans are favored by 3.5 points at DraftKings Sportsbook.
Sunday’s other biggest spreads include the Rams (-10.5) vs. Panthers, 49ers vs. Eagles (-4.5) and Chargers vs. Patriots (-3.5). The smallest Wild Card Weekend spreads include Packers (-1.5) vs. Bears and Bills (-1) vs. Jaguars. Top seeds Seattle in the NFC and Denver in the AFC have a bye week.
Before making any NFL picks for Wild Card Weekend 2026 or NFL score predictions on these or other games, you need to view the NFL vs. Spread, Over/Under and Moneyline Predictions powered by SportsLine’s self-learning AI.
Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine’s Data Science team, AI predictions and AI ratings are generated for each game. AI predictions are determined by learning statistically from each team’s historical data and then quantitatively assessing the strength of the opponent’s defense by assigning a numerical value out of 100 called a match score. It continually updates with the most recent data available and can help you spot the biggest gaps in lines. SportsLine’s AI PickBot has reached over 2,000 4.5 and 5 star prop picks since the start of the 2023 season.
For the Wild Card weekend NFL bettingSportsLine AI evaluated the NFL odds and provided NFL betting picks for all six games. You can only see the AI predictions for the Wild Card Weekend 2026 NFL schedule here.
Top NFL AI Picks for Wild Card Weekend 2026
After analyzing every game from Wild Card Weekend, the AI says the Steelers (+3, 39.5), who outlasted Baltimore in Week 18 to win the AFC North, are covering for a close loss.
The Texans have gone over in three of their last four games, while the over has scored in four of the Steelers’ last five games. Bet over 39.5 in the last DraftKings promo codewhich offers $300 bonus bets if your first bet wins:
Pittsburgh has won four of the last six meetings with Houston and is expected to cover in a close game. The Steelers, who will get receiver DK Metcalf back from suspension, are looking to win their first playoff game since reaching the AFC Championship Game in 2016. Houston won the last meeting, 30-6, on Oct. 1, 2023. SportsLine AI rates the Steelers as a B money line pick and also predicts a 22-21 Texans win on average. See its other 2026 Wild Card Weekend football predictions and football picks at SportsLine, and bet the Steelers at DraftKings here:
How to make 2026 Wild Card Weekend NFL picks
In addition, the AI PickBot has generated more than two dozen highly-coveted A picks for 2026 Wild Card Weekend. You need to see the AI’s NFL picks before making any 2026 Wild Card Weekend NFL bets of your own. You can only see them at SportsLine.
Who wins and covers each 2026 Wild Card Weekend NFL game, and which A+ picks should you target now? Visit SportsLine now to see the top NFL picks against the spread, over-under and on the money line, all from the SportsLine AI that has nailed more than 2,000 highly-rated picks since the start of the 2023 season.
