ADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites

Proceedings of the National Academy of Sciences, Volume 123, Number 2, January 2026.
Significance A-to-I RNA editing by adenosine deaminases acting on RNA (ADAR) enzymes reshapes the transcriptome and holds great promise for the design of therapeutic RNAs, but identification of edited adenosines remains a central challenge. We present Adar-GPT,…